HPLC-free Peptide
Purification
with Belyntic’s Catch & Release Technology
Test-Kit available now!
less solvent
consumption in comparison to HPLC
time savings
with eight peptides purified in parallel
selectivity
due to Belyntic’s linker molecules
Research Kit
ready to use
Run your purification of chemically synthesized peptides anywhere and without costly instruments. Belyntic’s Research Kit offers a high degree of comfort, providing a straightforward protocol to make the best out of your peptides.
-
all-in-one package (fritted cartridges equipped with filter media, purification linker and buffer salts)
-
parallel purification
-
high yields
-
various kit sizes (8×100 µmol, 8×25 µmol and 24×10 µmol)
Developer Kit
flexible integration
We help you to bring your purification throughput to the next level.
Integrate Belyntic’s technology in your processes and reduce time expenditure and resources.
-
basic materials (filter media and purification linker)
-
easy integration
-
high reliability
-
advanced throughput
-
scalable for bulk and API purification
Our Technology
Catch & Release Filtration
How it works, step by step:
Let's purify!
+
capping
amino acid coupling
· common Solid Phase Peptide Synthesis
· capping with Ac₂O after each amino
acid coupling is crucial
· purification linker is added
as the last amino acid
· high stability in DMF,
96% after 14 days
· can be coupled on synthesizer
· coupling yields: 80 - 100%
· after linker coupling common
TFA-cleavage can be performed
· in the resulting peptide mix,
only your desired peptide will
bear the purification linker
· organic solvents (e.g. DMSO) and
chaotropic salts (e.g. Gdn*HCl, Urea)
can be used for dissolution
of the peptides
· immobilization by oxime ligation
in less than 30 min
· on agarose or cellulose
· almost no unwanted adsorption
· flexible washing protocol with pure
water, buffers and/or organic solvents,
run-time around 10 minutes
· release by basic or reductive
stimulus ~ 30 min
← purified peptides, ready to use
Who is Belyntic?
Dr. Robert Zitterbart
Peptide chemist
Research & Development
Inventor of PEC
Dr. Oliver Reimann
Peptide chemist
Operations
Andreas Regnery
Economist
Finances
Dominik Sarma
Material chemist
Communications
Contact us
Belyntic’s team is dedicated to bring peptide purification to the next level. Don’t hesitate to contact us for information and inquiries.
