Belyntic's Peptide Easy Clean (PEC) technology breaks barriers in peptide manufacturing. We designed a catch-and-release methodology based on novel traceless cleavable linker molecules (PEC-Linkers) and activated filter materials for the purification and modification of chemically synthesized peptides.
Belyntic manufactures these innovative PEC-Linkers and offers you the first broadly applicable peptide purification kits together with related consumables to provide you with quick access to the technology.
We designed the Developer Kit to let purification be integrated flexibly in various workflows and projects. Throughput and scale are adjustable. The kit comes with the essential materials (PEC-Linker, activated filter material) along with a manual.
Our High-Throughput Kits open doors for the massive parallelization of peptide manufacturing. Create purified peptide libraries in the preparative scale using catch-and-release purification methodologies in 48- or 96-well filter plates.
The core of Belyntic's technological innovation is a catch-and-release methodologies with novel PEC-Linkers and activated filter materials, which enable several benefits for you:
“For the first time, the Belyntic PEC Kit enabled us to provide peptides that we couldn't purify before.”
Dr. Adrian Glas
Peptide Specialty Laboratories GmbH (PSL)
“[…] our collaboration has highlighted the potential of PEC in either single-step purification or as a pre-LC clean-up step for very complex crude peptide mixtures, making it a valuable addition to our toolbox. The flexible nature of the PEC purification method also provides an additional platform for more unusual peptide chemistry […]”
Dr. Gavin Noble
“With Belyntic's PEC technology, a set of 48 short peptides were rapidly provided, that we were able to use immediately for the development and validation of LC-MS/MS quantification methods. Their team was extremely helpful and responsive. They helped us move a novel project forward very quickly.”
Dr. Alex Kentsis
Memorial Sloan Kettering Cancer Center
“[…] The time saved is precious, enabling technicians to work on other tasks. Also, Belyntic has offered fantastic customer support, with fast communication and great suggestions on how to solve issues to achieve the highest yield and purity.”
Dr. Jonas E. Jensen
“The PEC linker is a significant new invention in peptide synthesis technology, and every peptide chemist can benefit from it. PEC enables all peptide-based biopharmaceutical businesses to considerably increase efficiency in terms of speed and cost of goods, and we expect it to become a standard method of art in peptide production technologies.”
Dr. Thomas Bruckdorfer (CSO & VP Business Development)
The absence of by-products and other impurities in peptide libraries, synthesized via SPPS, is vital for reliable assay results. However, especially in screenings (N > 24), crude peptides are often used because parallel purification of peptides is not feasible. We overcome this bottleneck by customi...Go to case study